The division is facilitated with Automated Ventana Immunostainers for immunohistochemistry
work, BD FACS Canto II eight colour Flow Cytometer for flow cytometry work and Eppendorf Thermal Cycler
for molecular biology work.
Clinical Activities :
The division evaluates 72 immunohistochemical
markers for differential histopathological
diagnosis, and predictive markers such as ER, PR
and Her-2-neu in breast cancer. By Flow cytometry
46 markers are being evaluated for
immunophenotyping of acute leukemia / CLPDs,
and for PNH and CD34 evaluation.
Academic Activities :
Cancer Biology department started MSc Cancer
Biology in affiliation to Gujarat University in July
2014. The division participates in teaching of MSc
Cancer Biology and enrolls PhD students. Post-graduates ( MSc / Mpharm ) from various
universities of Gujarat enrolled for dissertation
work and MSc and MDS students as observers..
Research Activities :
The main areas of research include study of PI3KAKT
pathway, and EMT pathway in breast cancer. Moreover, evaluation of circulating tumor cells and
cancer stem cells are evaluated by Flow Cytometry
in breast cancer patients. Further, a project is
proposed on molecules that influence cancer stem
cell niche in breast cancer. Minimal Residual
Disease is evaluated by flow cytometry and using
molecular markers in B-ALL. EGFR downstream
signaling pathway in non-smoker adenocarcinoma
of lung and immune dysfunction in oral cancer are
also being studied. Based on above research areas 7
research projects are ongoing in our division.