Facility Available : Next Generation Sequencing, Molecular set-up for DNA, RNA and protein based assays, Real-time PCR, Light Microscope, Microtome, Refrigerated centrifuge.
 

 
Clinical Services :

Oncomine Precision Assay (DNA+RNA) for solid tumors on NGS Platform; Genexus-A Fully Automated Integrated Sequencer.

Academic Activities :

The lab actively contributes to academic activities and training programs. It supports the M.Sc. Cancer Biology Course, including supervision of student dissertations, and provides molecular training to Oncopathology faculties and DM students. The laboratory also serves as a training and observation center for students from various disciplines, including M.Sc., M.Pharm, MDS, and MD programs from other universities and institutes.

Research Activities :

The laboratory is working on developing and validating a custom-targeted gene panel for diffuse glioma using NGS platform. This study aims to optimize molecular profiling for better diagnosis, prognosis, and treatment strategies for glioma patients.

Additionally, the lab is studying the role of the STAT3 Signaling Pathway and its association with microenvironment of glioma tumors aiming to identify potential biomarkers and therapeutic targets for patients with brain tumors. Separately, research on Autophagy Regulatory Genes focuses on its regulation in tumor cells, exploring its impact on glioma survival and progression, with the goal of targeting autophagy for new treatment options.

Strength/Workload:
Diagnostics: Molecular Diagnostics work for solid tumors using NGS platform
Research: Adults and Peadiatric Brain/CNS tumors and Cancer of Oral Cavity
Academic: M Sc. Cancer Biology (Post Graduation) Course in affiliation with Gujarat University. Ph. D. Guiding Teacher. Training DM students, Oncopathology Department, GCRI

Area of Interest: Brain/CNS Tumors