Facility Available : Molecular set-up for DNA, RNA and protein based assays, Real-time PCR, Light Microscope, Microtome, Refrigerated centrifuge.
 

 
Clinical Services Offered :

IDH1 R132H mutation by real time PCR
IDH1/2 Mutations by real-time PCR
MGMT Promoter Methylation by MS real-time PCR

Academic Activities :

The Lab is involved in M. Sc. Cancer Biology Course, Dissertation of M. Sc Cancer Biology students, Molecular training of Oncopathology faculties/staff and DM students, Finishing school activities and M. Sc, M. Pharm, MDS and MD students as observers from other Universities and/or Institutes.

Research Activities :

Research projects based on various molecular signaling pathways WNT pathway, Hedghog pathway, Notch signaling pathway, STAT-EGFR signaling pathways and Autophagy regulating pathways for gliomas and Medulloblastoma patients, study of H3F3A mutation and copy number variations of NMYC and ALK using droplet digital PCR for patients with brainstem glioma and neuroblastoma tumors, respectively. From cell-free DNA samples, IDH mutation and MGMT promoter methylation study for patients with diffuse glioma and high grade glioma tumors.

Strength/Workload:
Diagnostics: Molecular diagnostics work for CNS tumors
Research: Adults and peadiatric brain/CNS tumors/Oral cavity Tumors
Academic: M Sc. Cancer Biology (Post Graduation) Course related work, Lectures guiding and training DM students, Oncopathology Department, GCRI

Area of Interest: Oral Cancer & Brain/CNS Tumors